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Yep, that's possible, though the best with any distro is to backup the .folders in your home partition and make a fresh install. This way, you'll get most of your settings preserved, have little to tinker with configuration and above all else, you get a clean system.
Well, not exactly the "best with any distro"
Rolling release based distros like Archlinux are made to be used that way.
And I simply love it
That also limits the possibility of making major changes, which is something Fedora is NOT about...
To each their own.
I see your point though, his statement was rather ignorant.