The Wine program for running Windows games/applications on Linux and other platforms can run on a number of different architectures, but Wine doesn’t handle the emulation of running Windows x86/x64 binaries on other architectures like 64-bit ARM or PowerPC. But that’s what the Wine-based Hangover is about with currently allowing those conventional Windows binaries to run on AArch64 (ARM64) and 64-bit POWER too.
Hangover started out with a focus on Windows x64 binaries on ARM64 in looking at the possible use-case of running Windows software on ARM mobile devices and more. This year with the help of Raptor Computing Systems there has been Hangover support added for IBM POWER 64-bit.
It would be really amazing if Linux on POWER could make use of WINE like regular x86 Linux users can. It’s a long way off, still, but progress is being made.